541 research outputs found
Staphylococcus aureus DivIB is a peptidoglycan-binding protein that is required for a morphological checkpoint in cell division
Bacterial cell division is a fundamental process that requires the coordinated actions of a number of proteins which form a complex macromolecular machine known as the divisome. The membrane-spanning proteins DivIB and its orthologue FtsQ are crucial divisome components in Gram-positive and Gram-negative bacteria respectively. However, the role of almost all of the integral division proteins, including DivIB, still remains largely unknown. Here we show that the extracellular domain of DivIB is able to bind peptidoglycan and have mapped the binding to its β subdomain. Conditional mutational studies show that divIB is essential for Staphylococcus aureus growth, while phenotypic analyses following depletion of DivIB results in a block in the completion, but not initiation, of septum formation. Localisation studies suggest that DivIB only transiently localises to the division site and may mark previous sites of septation. We propose that DivIB is required for a molecular checkpoint during division to ensure the correct assembly of the divisome at midcell and to prevent hydrolytic growth of the cell in the absence of a completed septum
Examining coupled-channel effects in radiative charmonium transitions
Coupled-channel effects due to coupling of charmonia to the charmed and
anticharmed mesons are of current interest in heavy quarkonium physics.
However, the effects have not been unambiguously established. In this paper, a
clean method is proposed in order to examine the coupled-channel effects in
charmonium transitions. We show that the hindered M1 radiative transitions from
the 2P to 1P charmonia are suitable for this purpose. We suggest to measure one
or more of the ratios Gamma(h_c'-->chi_{cJ} gamma)/Gamma(chi_{cJ}'-->chi_{cJ}
pi^0) and Gamma(chi_{cJ}'-->h_c gamma)/Gamma(chi_{cJ}'-->chi_{cJ} pi^0), for
which highly nontrivial and parameter-free predictions are given. The picture
can also be tested using both unquenched and quenched lattice calculations.Comment: 5 pages, 2 figures. Numerical results corrected. Accepted for
publication in Phys. Rev. Let
A new photon recoil experiment: towards a determination of the fine structure constant
We report on progress towards a measurement of the fine structure constant to
an accuracy of or better by measuring the ratio of the
Planck constant to the mass of the cesium atom. Compared to similar
experiments, ours is improved in three significant ways: (i) simultaneous
conjugate interferometers, (ii) multi-photon Bragg diffraction between same
internal states, and (iii) an about 1000 fold reduction of laser phase noise to
-138 dBc/Hz. Combining that with a new method to simultaneously stabilize the
phases of four frequencies, we achieve 0.2 mrad effective phase noise at the
location of the atoms. In addition, we use active stabilization to suppress
systematic effects due to beam misalignment.Comment: 12 pages, 9 figure
Two-Photon Doppler cooling of alkaline-earth-metal and ytterbium atoms
A new possibility of laser cooling of alkaline-earth-metal and Ytterbium
atoms using a two-photon transition is analyzed. We consider a -
transition, with excitation in near resonance with the
level. This greatly increases the two-photon transition rate, allowing an
effective transfer of momentum. The experimental implementation of this
technique is discussed and we show that for Calcium, for example, two-photon
cooling can be used to achieve a Doppler limit of 123 microKelvin. The
efficiency of this cooling scheme and the main loss mechanisms are analyzed.Comment: 7 pages, 5 figure
Exact Occupation Time Distribution in a Non-Markovian Sequence and Its Relation to Spin Glass Models
We compute exactly the distribution of the occupation time in a discrete {\em
non-Markovian} toy sequence which appears in various physical contexts such as
the diffusion processes and Ising spin glass chains. The non-Markovian property
makes the results nontrivial even for this toy sequence. The distribution is
shown to have non-Gaussian tails characterized by a nontrivial large deviation
function which is computed explicitly. An exact mapping of this sequence to an
Ising spin glass chain via a gauge transformation raises an interesting new
question for a generic finite sized spin glass model: at a given temperature,
what is the distribution (over disorder) of the thermally averaged number of
spins that are aligned to their local fields? We show that this distribution
remains nontrivial even at infinite temperature and can be computed explicitly
in few cases such as in the Sherrington-Kirkpatrick model with Gaussian
disorder.Comment: 10 pages Revtex (two-column), 1 eps figure (included
Low noise amplication of an optically carried microwave signal: application to atom interferometry
In this paper, we report a new scheme to amplify a microwave signal carried
on a laser light at =852nm. The amplification is done via a
semiconductor tapered amplifier and this scheme is used to drive stimulated
Raman transitions in an atom interferometer. Sideband generation in the
amplifier, due to self-phase and amplitude modulation, is investigated and
characterized. We also demonstrate that the amplifier does not induce any
significant phase-noise on the beating signal. Finally, the degradation of the
performances of the interferometer due to the amplification process is shown to
be negligible
Magnetic trapping of metastable atomic strontium
We report the magnetic trapping of metastable atomic strontium. Atoms
are cooled in a magneto-optical trap (MOT) operating on the dipole allowed
transition at 461 nm. Decay via
continuously loads a magnetic trap formed by the quadrupole magnetic field of
the MOT. Over atoms at a density of cm and
temperature of 1 mK are trapped. The atom temperature is significantly lower
than what would be expected from the kinetic and potential energy of atoms as
they are transferred from the MOT. This suggests that thermalization and
evaporative cooling are occurring in the magnetic trap.Comment: This paper has been accepted by PR
Toward scalable quantum computation with cavity QED systems
We propose a scheme for quantum computing using high-Q cavities in which the
qubits are represented by single cavity modes restricted in the space spanned
by the two lowest Fock states. We show that single qubit operations and
universal multiple qubit gates can be implemented using atoms sequentially
crossing the cavities.Comment: 14 pages, 8 figure
Schur functions and their realizations in the slice hyperholomorphic setting
we start the study of Schur analysis in the quaternionic setting using the
theory of slice hyperholomorphic functions. The novelty of our approach is that
slice hyperholomorphic functions allows to write realizations in terms of a
suitable resolvent, the so called S-resolvent operator and to extend several
results that hold in the complex case to the quaternionic case. We discuss
reproducing kernels, positive definite functions in this setting and we show
how they can be obtained in our setting using the extension operator and the
slice regular product. We define Schur multipliers, and find their co-isometric
realization in terms of the associated de Branges-Rovnyak space
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